Current use of bypassing agents in Japan in patients with congenital hemophilia and inhibitors
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چکیده
منابع مشابه
Cost Components of Treatment Protocols of Haemophilia Patients with Inhibitors using Bypassing Agents in Iran
Bypassing agents are the most commonly used medicines for the treatment of hemophilia patients with inhibitors. The aim of this study is to identify the cost components of management of bleeding vents in hemophilia patients with inhibitors in Iran. This study is a cross-sectional study using a bottom-up approach to determine the cost components of treatment of hemophilia patients with inh...
متن کاملEfficacy of bypassing agents in patients with hemophilia and inhibitors: a systematic review and meta-analysis.
BACKGROUND Activated prothrombin complex concentrate (aPCC) and recombinant Factor VIIa (rFVIIa) are 2 bypassing agents commonly used for treating acute bleeds in hemophiliac patients with inhibitors. A wide range of efficacy rates for aPCC and rFVIIa have been reported in a number of single-armed and randomized controlled comparative studies. OBJECTIVE The aims of this study were to compare ...
متن کاملThe efficacy of bypassing agents in surgery of hemophilia patients with inhibitors
BACKGROUND Inhibitory antibodies to factor VIII (FVIII) or IX (FIX) are important issues when managing patients with hemophilia A or B. Advances in bypassing agents such as recombinant activated FVII (rFVIIa) and activated prothrombin complex concentrates (APCC) have enabled the aggressive management of hemophilia with inhibitors during emergency or elective surgery. This study provides an upda...
متن کاملHow I use bypassing therapy for prophylaxis in patients with hemophilia A and inhibitors.
Inhibitor development poses a significant challenge in the management of hemophilia because once an inhibitor is present, bleeding episodes can no longer be treated with standard clotting factor replacement therapy. Consequently, patients with inhibitors are at increased risk for difficult-to-control bleeding and complications, particularly arthropathy and physical disability. Three clinical tr...
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ژورنال
عنوان ژورنال: Japanese Journal of Thrombosis and Hemostasis
سال: 2007
ISSN: 1880-8808,0915-7441
DOI: 10.2491/jjsth.18.627